Myoblast Protection by Polyethylene Oxide-Polypropylene Oxide Block Copolymers against Hypo-Osmotic Stress
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چکیده
منابع مشابه
Protection against osmotic stress by cGMP-mediated myosin phosphorylation.
Conventional myosin functions universally as a generator of motive force in eukaryotic cells. Analysis of mutants of the microorganism Dictyostelium discoideum revealed that myosin also provides resistance against high external osmolarities. An osmo-induced increase of intracellular guanosine 3',5'-monophosphate was shown to mediate phosphorylation of three threonine residues on the myosin tail...
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Osmoregulation is important to living organisms for survival in responding to environmental changes ofwater and ionic strength. We demonstrated here for the first time that exposure of HeLa cells to a hypotonic medium (30% growth medium and 700% water) prominently induced the binding activity of the heat shock transcription factor (HSF). Pretreatment of cells with cycloheximide did not inhibit ...
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The solution properties of water-soluble amphiphiles in nonaqueous polar solvents are important in the elucidation of the effects of solvent quality on self-assembly and also in practical applications where the use of water as a solvent is undesirable. We studied the self-assembly of a poly(ethylene oxide)-poly(propylene oxide) (PEO-PPO) block copolymer (Pluronic P105: EO37PO58EO37) in formamid...
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Anionic polymerization has been used as a technique for the synthesis of five-block copolymers of polystyrene (PS), polyisoprene (PI), and poly(ethy1ene oxide) (PEO). Two types of such polymers, PEO-PI-PS-PI-PEO and PEO-PS-PI-PS-PEO with varying PEO block length, have been prepared, using potassium naphthalene as the initiator and tetrahydrofuran as the solvent. The polymers were purified by ex...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2018
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2017.11.2003